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Atovaquone/Proguanil

Drug Class: Commonly Known As: Category:
Antimalarial Malarone Adult, Children

Atovaquone/Proguanil - Dosage and How to Use

How should Atovaquone/Proguanil be used?

  • ​The medication is usually taken once a day, preferably at the same time of the day.
  • This medication should be taken with food or a milky drink.
  • Check with your pharmacist or doctor for the correct dose if you weigh less than 40kg.
  • Start one to two days before leaving the country and continue to take the medication every day during the trip.  After leaving the area with malaria risk, continue to take the medication daily and for one week after travel or once you return to Singapore. It is important to complete the full course for complete protection.
  • If you find it difficult to swallow the tablets, you can crush or mix the medication with small amounts of water, milk or other beverages.
  • Do not stop taking your medication before checking with your healthcare professional.

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and go back to your usual schedule. Do not take two doses to make up for the missed dose.

What should I do if I overdose?

Atovaquone/Proguanil - Additional Information

To prevent malaria, you may protect yourself against mosquito bites by:

  • Wearing long-sleeved clothing and long trousers between sunset and sunrise.
  • Applying insect repellent containing more than 20% DEET (N-Diethyl-meta-toluamide) for adults or 10% and less DEET for children on exposed skin. DEET is a common active ingredient in mosquito repellents.
  • Using mosquito coils in the room at night.
  • Sleep with mosquito nets around your bed, with the net edges tucked under the bed or sleep in a screened room.
  • Spray insecticide where mosquitos may rest. Mosquito larvae survive well in clear, slow-flowing streams.
  • Avoid going to an area where malaria is common.

Following these guidelines and medication does not mean that you will not get malaria. If you have a fever or experience chills between 1 week and up to 1 year after your return, you should seek medical attention. Inform the doctor that you have been to a country where malaria is common. Malaria can be effectively treated if discovered early. A delay in treatment may result in serious health problems.

  • Updated on Monday, September 30, 2019
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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