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Lapatinib

Drug Class: Commonly Known As: Category:
Dual Kinase Inhibitor Tykerb® Cancer-related

Lapatinib - Side Effects, Precautions, and Contraindications

What side effects can Lapatinib cause?

  • Nausea and vomiting
  • Diarrhea
  • Palms of the hands or soles of the feet may become numb, sore, red or dry
    Especially if Lapatinib is taken together with Capecitabine.
  • Rash, dry skin, itch
  • Tiredness and lack of energy

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher
  • Sores or ulcers in mouth and throat
  • Unusual bleeding, bruising or black tarry stools
  • Rapid or irregular heartbeat
  • Chest pain, cough or shortness of breath
  • Unusual water retention or swelling of the hands or feet
  • Yellowing of the skin or eyes or dark tea-coloured urine
  • Side effects become severe

Before taking Lapatinib, what precautions must I follow?

  • Use effective birth control during treatment with Lapatinib. Inform your doctor if you suspect pregnancy.
  • Inform your doctor or pharmacist if you are taking any other medication or supplements.

What food or medicine must I avoid when I take Lapatinib?

Avoid taking grapefruit or its juice while you are on Lapatinib.​

Lapatinib - Additional Information

  • Updated on Thursday, February 28, 2019
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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