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Tadalafil (Erectile Dysfunction)

Drug Class: Commonly Known As: Category:
Phosphodiesterase Type 5 Inhibitor Cialis

Tadalafil (Erectile Dysfunction) - What is it for

​Tadalafil is used to treat erectile dysfunction, a condition where you are unable to get or keep an erection firm enough to have sexual intercourse. It works by relaxing the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. This medicine will only help you to get an erection if you are sexually stimulated. Therefore it is taken on an as-needed basis.

It can also be used for urinary symptoms associated with benign prostatic hyperplasia (enlarged prostate) with or without erectile dysfunction at the same time. It improves blood flow to, and relaxes the muscles of the prostate and bladder which may reduce symptoms of benign prostatic hyperplasia. For this indication, it has to be taken on a daily basis.

This medication may also be used for other conditions. Check with your healthcare professional if you are unsure why you are given this medication.

Tadalafil (Erectile Dysfunction) - Side Effects, Precautions, and Contraindications

What side effects can Tadalafil (Erectile Dysfunction) cause?

  • ​Facial flushing where the skin on your face feels hot
  • Headache
  • Nausea
  • Back pain, muscle aches, pain in arms and legs
  • Nasal congestion

Priapism (an erection that will not go away) - If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis.

Sudden vision loss in one or both eyes - Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION).

Sudden hearing decrease or hearing loss - Some people may also have ringing in their ears (tinnitus) or dizziness.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Tadalafil (Erectile Dysfunction), what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication
  • You are taking medicines called Nitrates (such as sublingual nitroglycerin (also known as Glycerin Trinitrate or GTN), Isosorbide Mononitrate or Isosorbide Dinitrate), as the combination may lead to a dangerous fall in your blood pressure. Nitrates must be withheld at least 24 hours after the last dose of Sildenafil or Vardenafil, and 48 hours after the last dose of Tadalafil.
    Tell your doctor if you are taking any of these medicines which are often given for relief of angina (chest pain).  If you are not certain, ask your healthcare professional.
  • You are taking medicines called Alpha-1 Blockers (such as Tamsulosin, Terazosin, Prazosin, Alfuzosin), as the combination may further lower your blood pressure. In order to reduce the chances of these symptoms occurring, you should be on a regular daily dose of your Alpha-1 blockers before you start drugs for erectile dysfunction.
  • You recently had a stroke or a heart attack, low blood pressure or uncontrolled high blood pressure
  • You have severe heart, liver or kidney  problem
  • You have certain rare inherited eye diseases (such as retinitis pigmentosa)
  • You have a stomach ulcer or bleeding problem
  • You have a deformity of your penis

What food or medicine must I avoid when I take Tadalafil (Erectile Dysfunction)?

​Avoid taking grapefruit,or grapefruit juice as they may interact with your medication and increase the risk of side-effects.

Drinking alcohol can temporarily weaken your ability to get an erection and may increase the blood pressure lowering effects of the medication, which can be dangerous. To get the maximum benefit from your medication, it is advisable not to drink excessive amounts of alcohol before taking this medication.

Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications or herbal remedies.

This includes certain medications such as:

  • Antibiotics
  • Anti-fungal medications
  • Medications used to treat human immunodeficiency virus (HIV) infection
  • Medications for epilepsy (fits)

Tadalafil (Erectile Dysfunction) - Dosage and How to Use

How should Tadalafil (Erectile Dysfunction) be used?

  • ​For the treatment of erectile dysfunction and enlarged prostate,
    • When taking this medication on an as-needed basis, it usually starts to work within 30 minutes and effective up to 36 hours before sexual activity.
    • When taking on a daily basis, take at approximately the same time daily without regard to timing of sexual activity.
    • This medication may be taken with or without food

What should I do if I miss a dose?

  • ​When taking this medication on an as-needed basis, do not take more than once a day.
  • When taking this medication on a daily basis, take the missed dose as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.
  • Do not take more than the dose prescribed to you.

What should I do if I overdose?

Tadalafil (Erectile Dysfunction) - Handling

How should I handle Tadalafil (Erectile Dysfunction) safely?

Tadalafil (Erectile Dysfunction) - Storage

How should I store Tadalafil (Erectile Dysfunction)?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

How should I dispose of Tadalafil (Erectile Dysfunction) safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Tadalafil (Erectile Dysfunction) - Additional Information

  • Updated on Monday, September 30, 2019
  • Article contributed by PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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