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Dr Lim Wen Yi

Dr Lim Wen Yi

BDS (Singapore)

MDS (Endodontics) (Singapore)


M Endo RCS (Edinburgh)



National Dental Centre Singapore

Specialty: Endodontics

Clinical Appointments

  • Consultant Endodontics, Department of Restorative Dentistry National Dental Centre SingaporeNational Dental Centre Singapore


​Dr Lim Wen Yi is a Consultant with the Endodontic Unit of the Restorative Department in the National Dental Centre. Dr Lim received her Bachelor of Dental Surgery from the National University of Singapore (NUS) Faculty of Dentistry in 2011 with Dean’s List in the third and final year of undergraduate dental school. Following which, she pursued specialty training in Endodontics and obtained her Master of Dental Surgery (MDS) from NUS in 2016. She was a recipient of the Society of Endodontists Singapore Medal for achieving a Distinction at the Final NUS MDS Conjoint Exams with Royal College of Surgeons Edinburgh.

Dr Lim began her research journey back when she was an endodontic resident where she pursued the learning of pulp histological techniques with the renown Dr Domenico Ricucci. Following the completion of her Master’s thesis on the histology of dental pulps indicated for vital pulp therapy, she persisted in her interest in this field of pulp biology. She was awarded the Oral Health ACP Budding Clinician Researcher Award to work with Professor David Becker on the study of a gap junction protein, Connexin 43, in dental pulps. Her doctorate research under Professor Becker allowed her to delve into the basic science and translational aspects of modulating connexin 43 in the treatment of pulpitis (dental pulp inflammation). Her research skillset includes clinical trials, wet-bench lab research and animal model studies (rodent/porcine). She received the IADR Pulp Biology and Regeneration Group Student Award in 2020 for her work in dental pulp therapeutics. She completed her PhD training with Professor Becker in 2022, and still maintains clinical practice in endodontics while concurrently being involved in research and academic/clinical teaching.


  • PhD (Singapore) 2023
  • ​MDS (Singapore) 2016
  • MRCS (Edinburgh) 2016
  • BDS (Singapore) 2011

Professional Appointments and Committee Memberships

  • Director, Clinical Research, Singhealth Oral Health Academic Clinical Programme
  • Vice President, Society of Endodontists Singapore
  • Member, Singhealth Investigational Medicine Unit Executive Committee


  • Singapore Health Services Quality Awards Gold (2023)
  • International Association for Dental Research Pulp Biology & Regeneration Group Student Award (2020)
  • Singapore Health Services Quality Awards Silver (2019, 2022)
  • Budding Clinician Researcher Award, National Dental Centre Singapore (2017-2020)
  • Society of Endodontists Singapore Gold Medal (2016)
  • Dean’s List, Faculty of Dentistry, National University of Singapore (2010 and 2011)
  • 1st Runner-up, Undergraduate Research Opportunity Programme, Faculty of Dentistry, National University of Singapore (2010)

Research Interests

  • ​Dental pulp inflammation and wound healing, biomarkers, vital pulp therapy, regenerative endodontics, pulp biology


  • Sim K, Lim WY, Wei CML, Yu VSH, Lui JN. Impact of endodontic disease on oral health-related quality of life in the elderly. Under review with Journal of Endodontics 2023.
  • Omer H, Fatma PH, Lim WY et al. Factors Affecting the Decision-Making of Direct Pulp Capping Procedures Amongst Dental Practitioners: A Multinational Survey from 16 Countries with Meta-Analysis. Epub J Endod 2023 doi:10/1016/j.joen.2023.04.005
  • Lim, WY (2022). Differential expression of Connexin 43 during dental pulp inflammation and its role in pulpal healing: a translational study determining effect of Connexin 43 downregulation in treatment of pulpitis. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/165279
  • Lim WY, Madden L, Becker DL. Pulpal upregulation of Connexin 43 in pulpitis. Clin Oral Investig 2021 Mar;25(3):1327-1335. doi: 10.1007/s00784-020-03439-6.
  • Lui JN, Lim WY, Ricuci D. An immunofluorescence study to analyze wound healing outcomes of regenerative endodontics in an immature premolar with chronic apical abscess J Endod 2020 May;46(5):627-640. doi: 10.1016/j.joen.2020.01.015.
  • Lim, WY (2016). Correlation of pulp histology with haemostatic control after partial pulpotomy (dissertation). National University of Singapore, Singapore.
  • Lim WY, Ode W, Tay CX, eds. Anatomical Challenges in Endodontics: Identification & Management. Faculty of Dentistry, Singapore, 2015. ISBN: 978-981-09-5137-5

Research Trials

  • Correlation between pulpal inflammatory markers and clinical outcomes of partial pulpotomy – Co-I
  • An analysis of persistent disease following modern endodontic microsurgery – Co-PI
  • Correlation of haemostatic control and pulp histology after partial pulpotomy – PI