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Lui Jeen Nee

Dr Lui Jeen Nee

  • Senior Consultant and Head, Endodontic Unit and Department of Restorative Dentistry, National Dental Centre Singapore
  • Associate Director, Endodontics Residency Training Programme, Faculty of Dentistry, National University of Singapore


In her role as Head, Endodontic Unit at NDCS, Dr Lui Jeen Nee is actively engaged in endodontic research and publishes actively as a principal investigator, co-investigator and collaborator. She has supervised over 10 endodontic residents for their Masters of Dental Surgery thesis. Her research focuses on endodontic microbiology, endodontic regeneration, vital pulp therapy, cracked teeth, endodontic microsurgery and treatment outcomes. As a practicing endodontist and researcher, her goal is for her research to translate to better clinical outcomes for patients.


Research Focus Areas

Endodontic microbiology, endodontic regeneration, vital pulp therapy, cracked teeth, endodontic microsurgery, treatment outcomes


Current Projects

  • A biomaterials approach for endodontic (dental pulp) regeneration
  • Role of connexin 43 in caries induced pulpitis
  • An analysis of persistent disease following modern endodontic microsurgery
  • Correlation between pulpal inflammatory markers and clinical outcomes of partial pulpotomy
  • Assessment of quality of life of non-surgically retreated and surgically treated endodontic patients: A mixed-method approach
  • Effect of waiting times in non-surgical root canal treatment and crown placement on long-term outcomes
  • Management of cracked teeth: A survey among dental practitioners in Singapore


Publications and/or Research Projects

  1. Lui JN, Lim WY, Ricucci D. An immunofluorescence study to analyze wound healing outcomes of regenerative endodontics in an immature premolar with chronic apical abscess. J Endod (accepted for publication)
  2. Huang S, Chen NN, Yu VSH, Lim HA, Lui JN. Long-term success and survival of endodontic microsurgery. J Endod 2020;46(2):149-57.
  3. Tay CX, Quah SY, Lui JN, Yu VS, Tan KS. Matrix metalloproteinase inhibitor as an antimicrobial agent to eradicate Enterococcus faecalis biofilm. J Endod 2015;41(6):858-63.
  4. Lew HP, Quah SY, Lui JN, Bergenholtz G, Hoon Yu VS, Tan KS. Isolation of alkaline-tolerant bacteria from primary infected root canals. J Endod 2015;41(4):451-6.
  5. Lui JN, Khin MM, Krishnaswamy G, Chen NN. Prognostic factors relating to the outcome of endodontic microsurgery. J Endod 2014;40(8):1071-6.
  6. Quah SY, Wu S, Lui JN, Sum CP, Tan KS. N-acetylcysteine inhibits growth and eradicates biofilm of Enterococcus faecalis. J Endod 2012;38(1):81-5.
  7. Kuah HG, Lui JN, Tseng PS, Chen NN. The effect of EDTA with and without ultrasonics on removal of the smear layer. J Endod 2009;35(3):393-6.     
  8. Lui JN, Kuah HG, Chen NN. Effect of EDTA with and without surfactants and ultrasonics on removal of smear layer. J Endod 2007;33(4):472-5.
  9. Lui JN, Sae-Lim V, Song KP, Chen NN. In vitro antimicrobial effect of chlorhexidine-impregnated gutta percha points on Enterococcus faecalis. Int Endod J 2004;37(2):105-13.