• IL-11 is a crucial determinant of cardiovascular fibrosis. Schafer S, Viswanathan S, Widjaja AA,
Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chotani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Tee NGZ, Xie C, Wang M, Maayz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimares-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA. Nature. 2017 Nov 13;552(7683):110-115.
• Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models. Lim WW, Corden B, Ng B, Vanezis K, D’Agostino G, Widjaja AA, Song WH, Xie C, Su L, Kwek XY, Tee NGZ, Dong J, Ko NSJ, Wang M, Pua CJ, Jamal MH, Soh B, Viswanathan S, Schafer S, Cook SA. Sci Rep. 2020 Oct 20;10:17853.
• Therapeutic targeting of interleukin-11 signalling reduces pressure overload–induced cardiac fibrosis in mice. Corden B*, Lim WW*, Song W, Chen X, Ko NSJ, Su L, Tee NGZ, Adami E, Schafer S, Cook SA. J Cardiovasc Transl Res. 2021 Jun 26;14(2):222-228. *Joint first author
• Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload. Lim WW, Corden B, Ye L, Viswanathan S, Widjaja AA, Xie C, Su L, Tee NGZ, Schafer S, Cook SA. Clin Exp Pharmacol Physiol. 2021 Apr;48(4):605-613.
• Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis. Ng B, Dong J, D’Agostino G, Viswanathan S, Widjaja AA, Lim WW, Ko NSJ, Tan J, Chothani SP, Huang B, Xie C, Pua CJ, Chacko AM, Guimarães-Camboa N, Evans SM, Byrne AJ, Maher TM, Liang J, Jiang D, Noble PW, Schafer S, Cook SA. Sci. Transl. Med. 2019 Sep 25;11(5):eaaw1237.
• Electrophysiological and Structural Remodeling of the Atria in a Mouse Model of Troponin-I mutation linked Hypertrophic Cardiomyopathy: Implications for Atrial Fibrillation. Lim WW, Neo M, Thanigaimani S, Kuklik P, Ganesan AN, Lau DH, Tsoutsman T, Kalman JM, Semsarian C, Saint DA, Sanders P. Int J Mol Sci. 2021 Jun 28;22(13):6941.
• Slowed atrial and atrioventricular conduction and depressed HRV in a murine model of hypertrophic cardiomyopathy. Lim WW, Baumert M, Neo M, Kuklik P, Ganesan AN, Lau DH, Tsoutsman T, Semsarian C, Sanders P, Saint DA. Clin Exp Pharmacol Physiol. 2016 Jan;43:95-101.
• Simultaneous conduction mapping and intracellular membrane potential measurement of action potential parameters in isolated atria. Neo M, Morris D, Kuklik P, Lau D, Dimitri H, Lim WW, Sanders P, Saint DA. Can J Physiol Pharmacol. 2016 May; 94(5):563-569.
• Bipolar Electrogram Shannon Entropy at Sites of Rotational Activation Implications for Ablation of Atrial Fibrillation. Ganesan AN, Kuklik P, Lau DH, Brooks AG, Baumert M, Lim WW, Thanigaimani S, Nayyer S, Mahajan R, Kalman JM, Roberts-Thomson KC, Sanders P. Circ Arrhythm Electrophysiol. 2013 Feb;6(1):48-57.
