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Alectinib

Drug Class: Commonly Known As: Category:
Anaplastic Lymphoma Kinase (ALK) Tyrosine Kinase Inhibitor Alecensa Cancer-related

Alectinib - Side Effects, Precautions, and Contraindications

What side effects can Alectinib cause?

Common side effects include:

  • Constipation
    • Drink more water or clear fluids (if you do not have a limit on the amount you can take each day).
    • Add more fibre to your diet by eating more fruits and vegetables.
  • Feeling tired and lack of energy
    • Do not drive or operate machinery when you feel tired.
  • Skin rash, sensitivity to sun
    • Avoid too much exposure to the sun. Use a sunscreen and lip balm that has a Sun Protection Factor (SPF) of 50 or more during treatment and for 7 days after the last dose of Alectinib.
  • Reduced red blood cell count

Rare but serious side effects include:

  • Sudden onset of cough, chest pain, shortness of breath or fever
  • Dark urine or light coloured stools, nausea, vomiting, loss of appetite, stomach pain, yellowing of your eyes or skin
  • Very bad swelling of hands, feet or lower legs
  • Passing out very little urine although you are taking similar amount of water and fluid everyday
  • Slow heartbeat
  • Unusual giddiness or light-headedness
  • Very bad muscle soreness or weakness that does not go away

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Alectinib, what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication.
  • You or your partner becomes pregnant or is planning for pregnancy
    • You should use effective birth control during and for 3 months after stopping Alectinib.
  • You are breastfeeding
    • Do not breastfeed during and for 1 week after stopping Alectinib.
  • You have any other medical conditions such as having slow heartbeat.

What food or medicine must I avoid when I take Alectinib?

​Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications or herbal remedies. Some of them may affect how Alectinib works.

Alectinib - Additional Information

​You may refer to the following website if you need more information: https://www.macmillan.org.uk/

  • Updated on Monday, September 30, 2019
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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